H1B Salary Data

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Natural Sciences Managers in South San Francisco, CA: H-1B salaries

37 labor condition applications for this occupation with a work site in South San Francisco, CA. Median offered base salary $193,170; middle half $161,508–$223,034.

Applications (LCAs)37
Median offered salary$193,170
Middle half of salaries$161,508–$223,034
10th–90th percentile$132,016–$258,669

By wage level

Wage levelMedian salary
Level I (entry)$170,000
Level II (qualified)$193,170
Level III (experienced)$249,105
Level IV (fully competent)$258,669

The Department of Labor sets four prevailing wage levels for each occupation and area, from Level I (entry) to Level IV (fully competent). The employer picks the level that matches the job's requirements.

Employers

EmployerLCAsMedian salary
Genentech, Inc.8$197,010
Denali Therapeutics Inc.4$225,017
Ideaya Biosciences Inc.3$161,508
Sutro Biopharma, Inc.3$205,500
GlaxoSmithKline LLC1$183,532
Twist Bioscience Corporation1$140,000
Vaxart, Inc.1$151,372
Freenome Holdings, Inc.1$220,000
Blue Matter Consulting LLC1$170,000
Nkarta, Inc.1$127,239
CytomX Therapeutics, Inc.1$193,170
Aligos Therapeutics, Inc.1$230,000
California Institute for Regenerative Medicine1$123,600
Neurona Therapeutics, Inc.1$107,434
Agrim Technologies Inc1$135,200
TheRas Inc.1$185,000
Calico Life Sciences LLC1$225,000
Assembly Biosciences, Inc.1$233,210
Spruce Biosciences, Inc.1$266,000
Abbvie Biotherapeutics Inc.1$209,000
Horizon Therapeutics USA, Inc.1$294,755
Amgen Inc.1$190,000
Mission Bio, Inc.1$170,000

Job titles

H-1B sponsors in South San Francisco, CA →

Salaries are the lower end of the wage offered on each application, converted to a yearly amount; statistics use certified full-time applications only. An LCA is not a visa approval and one LCA can cover several positions. Source: U.S. Department of Labor, OFLC LCA Disclosure Data, fiscal years 2023–2026 (latest decision Jun 30, 2026).